Interactions médicamenteuses
Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal
Gravité: Contre-indiquée
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
Ce que signifie cette interaction, en termes simples
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
TNF blockade-related immunosuppression reduces control of replicating attenuated influenza virus.
Conduite à tenir
Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Certolizumab pegol et Influenza virus vaccine quadrivalent intranasal, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contre-indiquée
- Bcg intravesical live + Certolizumab pegol Contre-indiquée
- Bcg vaccine live + Certolizumab pegol Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine Contre-indiquée
- Certolizumab pegol + Measles mumps and rubella vaccine live Contre-indiquée
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Certolizumab pegol with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
How serious is the interaction between Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
