Interactions médicamenteuses
Entecavir + Foscarnet
Gravité: Modérée
Entecavir and Foscarnet: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Foscarnet is nephrotoxic and entecavir is eliminated mainly by the kidney, so reduced renal function could raise entecavir levels. Entecavir is also secreted by tubular transport, though a direct competition effect with foscarnet is not well documented.
Ce que signifie cette interaction, en termes simples
Entecavir and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Entecavir belongs to Anti Virals; Foscarnet belongs to Anti Virals.
Pourquoi elle survient
Foscarnet-related renal impairment may reduce renal clearance of entecavir; competition for tubular secretion is possible but unproven.
Conduite à tenir
Monitor serum creatinine during foscarnet therapy and adjust the entecavir dose to creatinine clearance. Watch for entecavir adverse effects such as lactic acidosis if renal function falls.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Entecavir et Foscarnet, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Foscarnet
- Cidofovir + Foscarnet Contre-indiquée
- Foscarnet + Pimozide Contre-indiquée
- Foscarnet + Thioridazine Contre-indiquée
- Foscarnet + Vandetanib Contre-indiquée
- Adagrasib + Foscarnet Majeure
- Adefovir + Foscarnet Majeure
Autres interactions de Entecavir
Questions fréquentes
Can I take Entecavir with Foscarnet?
MediHelp rates the interaction as moderate. Entecavir and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet is nephrotoxic and entecavir is eliminated mainly by the kidney, so reduced renal function could raise entecavir levels. Entecavir is also secreted by tubular transport, though a direct competition effect with foscarnet is not well documented.
How serious is the interaction between Entecavir and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine during foscarnet therapy and adjust the entecavir dose to creatinine clearance. Watch for entecavir adverse effects such as lactic acidosis if renal function falls.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
