Aller au contenu

Interactions médicamenteuses

Ciprofloxacin + Sodium bicarbonate

Gravité: Modérée

Ciprofloxacin and Sodium bicarbonate: moderate interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Alkalinizing agents raise urinary pH and can reduce ciprofloxacin solubility, increasing the chance of crystalluria. Antacid effects may also slightly reduce absorption of oral ciprofloxacin.

Ce que signifie cette interaction, en termes simples

Ciprofloxacin and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ciprofloxacin belongs to Anti Bacterial; Sodium bicarbonate belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Decreased urinary solubility of ciprofloxacin in alkaline urine, with possible reduced gastric absorption.

Conduite à tenir

Maintain good hydration and monitor renal function and urinalysis for crystalluria. Take ciprofloxacin at least 2 hours before the bicarbonate.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Ciprofloxacin et Sodium bicarbonate, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.

Questions fréquentes

Can I take Ciprofloxacin with Sodium bicarbonate?

MediHelp rates the interaction as moderate. Ciprofloxacin and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alkalinizing agents raise urinary pH and can reduce ciprofloxacin solubility, increasing the chance of crystalluria. Antacid effects may also slightly reduce absorption of oral ciprofloxacin.

How serious is the interaction between Ciprofloxacin and Sodium bicarbonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain good hydration and monitor renal function and urinalysis for crystalluria. Take ciprofloxacin at least 2 hours before the bicarbonate.

What other medicines interact with Ciprofloxacin?

MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter