Interactions médicamenteuses
Delafloxacin + Magnesium sulphate
Gravité: Modérée
Delafloxacin and Magnesium sulphate: moderate interaction.
Dernière mise à jour
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Résumé
Oral magnesium salts can bind delafloxacin in the gut, forming chelates that are poorly absorbed. This can lower delafloxacin concentrations and risk treatment failure. The concern applies to oral magnesium products, not intravenous magnesium.
Ce que signifie cette interaction, en termes simples
Delafloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Magnesium sulphate belongs to Cardiovascular.
Pourquoi elle survient
Chelation of delafloxacin by divalent magnesium cations in the gastrointestinal tract reduces its absorption.
Conduite à tenir
Give oral delafloxacin at least 2 hours before or 6 hours after oral magnesium-containing products.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Magnesium sulphate
Autres interactions de Delafloxacin
- Aluminum hydroxide + Delafloxacin Modérée
- Calcium carbonate + Delafloxacin Modérée
- Calcium + Delafloxacin Modérée
- Carbonyl iron + Delafloxacin Modérée
- Delafloxacin + Didanosine Modérée
- Delafloxacin + Ferrous fumarate Modérée
Questions fréquentes
Can I take Delafloxacin with Magnesium sulphate?
MediHelp rates the interaction as moderate. Delafloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium salts can bind delafloxacin in the gut, forming chelates that are poorly absorbed. This can lower delafloxacin concentrations and risk treatment failure. The concern applies to oral magnesium products, not intravenous magnesium.
How serious is the interaction between Delafloxacin and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after oral magnesium-containing products.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
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