Aller au contenu

Interactions médicamenteuses

Ciprofloxacin + Magnesium sulphate

Gravité: Modérée

Ciprofloxacin and Magnesium sulphate: moderate interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.

Ce que signifie cette interaction, en termes simples

Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ciprofloxacin belongs to Anti Bacterial; Magnesium sulphate belongs to Cardiovascular.

Niveau de preuve: High

Pourquoi elle survient

Chelation of ciprofloxacin by divalent magnesium cations in the gastrointestinal tract forms poorly absorbed complexes.

Conduite à tenir

Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Ciprofloxacin et Magnesium sulphate, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Ciprofloxacin with Magnesium sulphate?

MediHelp rates the interaction as moderate. Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.

How serious is the interaction between Ciprofloxacin and Magnesium sulphate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.

What other medicines interact with Magnesium sulphate?

MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter