Aller au contenu
MediHelp
MediHelp Référence médicamenteuse

Interactions médicamenteuses

Eletriptan + Nelfinavir

Gravité: Contre-indiquée

Eletriptan and Nelfinavir: contraindicated interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Nelfinavir strongly inhibits CYP3A4 and increases eletriptan plasma levels. Greater exposure increases the risk of vasoconstrictive cardiovascular adverse effects.

Ce que signifie cette interaction, en termes simples

Eletriptan and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Eletriptan belongs to Central Nervous System; Nelfinavir belongs to Anti Virals.

Niveau de preuve: High

Pourquoi elle survient

Inhibition of CYP3A4-mediated metabolism of eletriptan.

Conduite à tenir

Do not co-administer; avoid eletriptan for at least 72 hours after nelfinavir. Use an alternative triptan such as rizatriptan or sumatriptan.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Eletriptan et Nelfinavir, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
Créer un compte gratuit Se connecter

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Eletriptan with Nelfinavir?

MediHelp rates the interaction as contraindicated. Eletriptan and Nelfinavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Nelfinavir strongly inhibits CYP3A4 and increases eletriptan plasma levels. Greater exposure increases the risk of vasoconstrictive cardiovascular adverse effects.

How serious is the interaction between Eletriptan and Nelfinavir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; avoid eletriptan for at least 72 hours after nelfinavir. Use an alternative triptan such as rizatriptan or sumatriptan.

What other medicines interact with Eletriptan?

MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Télécharger surApp Store Disponible surGoogle Play

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter