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Interactions médicamenteuses

Eletriptan + Rizatriptan

Gravité: Contre-indiquée

Eletriptan and Rizatriptan: contraindicated interaction.

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Résumé

Eletriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary arteries. Used within a day of each other their vasoconstriction is additive, with risk of coronary spasm and raised blood pressure.

Ce que signifie cette interaction, en termes simples

Eletriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Eletriptan belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.

Niveau de preuve: High

Pourquoi elle survient

Additive 5-HT1B/1D-mediated vasoconstriction

Conduite à tenir

Do not use two triptans within 24 hours; limit each attack to one triptan.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Eletriptan with Rizatriptan?

MediHelp rates the interaction as contraindicated. Eletriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eletriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary arteries. Used within a day of each other their vasoconstriction is additive, with risk of coronary spasm and raised blood pressure.

How serious is the interaction between Eletriptan and Rizatriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use two triptans within 24 hours; limit each attack to one triptan.

What other medicines interact with Rizatriptan?

MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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