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Interactions médicamenteuses

Ephedrine + Ergotamine

Gravité: Majeure

Ephedrine and Ergotamine: major interaction.

Dernière mise à jour

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Résumé

Ephedrine is a sympathomimetic with pressor and vasoconstrictor effects. Combined with ergotamine it may cause excessive vasoconstriction, severe hypertension and ischemia.

Ce que signifie cette interaction, en termes simples

Ephedrine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ephedrine belongs to Cardiovascular; Ergotamine belongs to Central Nervous System.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive alpha-adrenergic and ergot-mediated vasoconstriction.

Conduite à tenir

Avoid the combination; if ephedrine is needed, monitor blood pressure and peripheral perfusion closely.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Ephedrine with Ergotamine?

MediHelp rates the interaction as major. Ephedrine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ephedrine is a sympathomimetic with pressor and vasoconstrictor effects. Combined with ergotamine it may cause excessive vasoconstriction, severe hypertension and ischemia.

How serious is the interaction between Ephedrine and Ergotamine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; if ephedrine is needed, monitor blood pressure and peripheral perfusion closely.

What other medicines interact with Ergotamine?

MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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