Interactions médicamenteuses
Folic acid + Pafolacianine
Gravité: Modérée
Folic acid and Pafolacianine: moderate interaction.
Dernière mise à jour
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Résumé
Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
Ce que signifie cette interaction, en termes simples
Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Competitive binding at folate receptors reduces pafolacianine uptake.
Conduite à tenir
Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Folic acid
- Ethotoin + Folic acid Modérée
- Folic acid + Fosphenytoin Modérée
- Folic acid + Glucarpidase Modérée
- Folic acid + Methotrexate Modérée
- Folic acid + Phenobarbital Modérée
- Folic acid + Phenytoin Modérée
Questions fréquentes
Can I take Folic acid with Pafolacianine?
MediHelp rates the interaction as moderate. Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
How serious is the interaction between Folic acid and Pafolacianine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
What other medicines interact with Folic acid?
MediHelp also lists interactions of Folic acid with, for example, Ethotoin, Fosphenytoin, Glucarpidase. The full list is on the Folic acid page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
