Aller au contenu

Interactions médicamenteuses

Ivacaftor + Micafungin

Gravité: Mineure

Ivacaftor and Micafungin: minor interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Ivacaftor is a sensitive CYP3A4 substrate, and micafungin may weakly inhibit CYP3A4 in vitro. A small increase in ivacaftor exposure is possible but not well documented clinically.

Ce que signifie cette interaction, en termes simples

Ivacaftor and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ivacaftor belongs to Miscellaneous; Micafungin belongs to Anti Fungals.

Niveau de preuve: Low

Pourquoi elle survient

Possible weak CYP3A4 inhibition by micafungin reducing ivacaftor metabolism.

Conduite à tenir

Dose adjustment is not required for weak inhibitors; monitor for ivacaftor adverse effects such as raised transaminases and headache.

Questions à poser à votre pharmacien

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Ivacaftor et Micafungin, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Ivacaftor with Micafungin?

MediHelp rates the interaction as minor. Ivacaftor and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ivacaftor is a sensitive CYP3A4 substrate, and micafungin may weakly inhibit CYP3A4 in vitro. A small increase in ivacaftor exposure is possible but not well documented clinically.

How serious is the interaction between Ivacaftor and Micafungin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Dose adjustment is not required for weak inhibitors; monitor for ivacaftor adverse effects such as raised transaminases and headache.

What other medicines interact with Micafungin?

MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter