Interactions médicamenteuses
Lithium + Sodium polystyrene sulfonate
Gravité: Modérée
Lithium and Sodium polystyrene sulfonate: moderate interaction.
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Résumé
Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.
Ce que signifie cette interaction, en termes simples
Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lithium belongs to Central Nervous System; Sodium polystyrene sulfonate belongs to Miscellaneous.
Pourquoi elle survient
Cation-exchange resin binds lithium in the gastrointestinal tract, reducing absorption.
Conduite à tenir
Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Lithium
- Lithium + Thioridazine Contre-indiquée
- Lithium + Vandetanib Contre-indiquée
- Aceclofenac + Lithium Majeure
- Acemetacin + Lithium Majeure
- Amisulpride + Lithium Majeure
- Amlodipine-benazepril + Lithium Majeure
Autres interactions de Sodium polystyrene sulfonate
- Meloxicam + Sodium polystyrene sulfonate Majeure
- Sodium polystyrene sulfonate + Sorbitol Majeure
- Calcium carbonate + Sodium polystyrene sulfonate Modérée
- Deflazacort + Sodium polystyrene sulfonate Modérée
- Levothyroxine + Sodium polystyrene sulfonate Modérée
- Magnesium citrate + Sodium polystyrene sulfonate Modérée
Questions fréquentes
Can I take Lithium with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.
How serious is the interaction between Lithium and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
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