Interactions médicamenteuses
Calcium carbonate + Sodium polystyrene sulfonate
Gravité: Modérée
Calcium carbonate and Sodium polystyrene sulfonate: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Sodium polystyrene sulfonate can bind calcium in the gut, and the antacid effect of calcium carbonate may be offset by cation exchange. Reduced binding of bicarbonate-producing cations has been associated with metabolic alkalosis, especially in renal impairment. Clinical impact is usually modest but can matter in dialysis patients.
Ce que signifie cette interaction, en termes simples
Calcium carbonate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
Pourquoi elle survient
Non-absorbed cation-exchange resin binds calcium and other cations in the gut, and combined with non-absorbable antacid it can leave bicarbonate unneutralized and cause systemic alkalosis.
Conduite à tenir
Separate administration by at least 3 hours (6 hours in gastroparesis) and monitor serum calcium, potassium and acid-base status in renal impairment.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Calcium carbonate et Sodium polystyrene sulfonate, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Calcium carbonate
Autres interactions de Sodium polystyrene sulfonate
Questions fréquentes
Can I take Calcium carbonate with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Calcium carbonate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate can bind calcium in the gut, and the antacid effect of calcium carbonate may be offset by cation exchange. Reduced binding of bicarbonate-producing cations has been associated with metabolic alkalosis, especially in renal impairment. Clinical impact is usually modest but can matter in dialysis patients.
How serious is the interaction between Calcium carbonate and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by at least 3 hours (6 hours in gastroparesis) and monitor serum calcium, potassium and acid-base status in renal impairment.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
