Référentiel des médicaments
Sodium polystyrene sulfonate
Sodium polystyrene sulfonate is a medicine in the class miscellaneous. It is used for hyperkalemia.
- Classe médicamenteuse: Miscellaneous
- Indications: hyperkalemia
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
L'essentiel
- Classe médicamenteuse
- Miscellaneous
- Formes courantes
- suspension buvable, poudre
- Dosages courants
- 15 g/60 ml, 454 g
- Interactions connues
- 11 (Majeure: 2 · Modérée: 7 · Mineure: 2)
- Noms commerciaux
- 2
- Pays et marchés
- 2
Indications
Mécanisme d'action
Cation exchange resin, sodium ions partially released from polystyrene and replaced by potassium
Posologie adulte habituelle (résumé de la notice)
Hyperkalemia PO: 15 g once daily or q6-12hr
Grossesse et allaitement
- Grossesse
- Safe Not absorbed after oral or rectal use, so maternal use is not expected to expose the fetus (US label). UK label: no data, use only if the benefit outweighs the risk. Monitor potassium, calcium and magnesium, and watch for constipation.
- Allaitement
- Safe Not absorbed by the mother, so it does not reach milk; no infant risk is expected (US label, LactMed). UK label: no data, use only if the benefit outweighs any risk. LactMed: no special precautions needed.
Effets indésirables signalés
- Sodium retention, Fluid retention.
- Constipation
- Hypokalemia
- Hypomagnesemia
- Nausea and Vomiting
Contre-indications
- Hypersensitivity to polystyrene sulfonate resins
- Hypokalemia
- Obstructive bowel disease
Précautions particulières
- Best when used in non-life-threatening hyperkalemia
- Hypokalemia may occur monitor serum potassium frequently within each 24 hr period; ECG monitoring may be appropriate in some patients; cation exchange resins may also affect concentrations of other cations, including calcium and magnesium
- Use caution with dosage forms containing propylene glycol; large amounts are potentially toxic; associated with hyperosmolality, seizures, lactic acidosis, and respiratory depression
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (11)
- Meloxicam + Sodium polystyrene sulfonate Major
- Sodium polystyrene sulfonate + Sorbitol Major
- Calcium carbonate + Sodium polystyrene sulfonate Moderate
- Deflazacort + Sodium polystyrene sulfonate Moderate
- Levothyroxine + Sodium polystyrene sulfonate Moderate
- Lithium + Sodium polystyrene sulfonate Moderate
- Magnesium + Sodium polystyrene sulfonate Moderate
- Magnesium citrate + Sodium polystyrene sulfonate Moderate
- Magnesium hydroxide + Sodium polystyrene sulfonate Moderate
- Calcium + Sodium polystyrene sulfonate Minor
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Questions fréquentes
What is Sodium polystyrene sulfonate used for?
Sodium polystyrene sulfonate is a medicine in the class miscellaneous. It is used for Hyperkalemia.
What side effects have been reported with Sodium polystyrene sulfonate?
Sodium retention, Fluid retention., Constipation, Hypokalemia, Hypomagnesemia, Nausea and Vomiting.
Can Sodium polystyrene sulfonate be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not absorbed after oral or rectal use, so maternal use is not expected to expose the fetus (US label). UK label: no data, use only if the benefit outweighs the risk. Monitor potassium, calcium and magnesium, and watch for constipation. Breastfeeding: Safe. Not absorbed by the mother, so it does not reach milk; no infant risk is expected (US label, LactMed). UK label: no data, use only if the benefit outweighs any risk. LactMed: no special precautions needed.
What does Sodium polystyrene sulfonate interact with?
MediHelp lists 11 known interactions for Sodium polystyrene sulfonate. Major: 2 · Moderate: 7 · Minor: 2. The most serious include Meloxicam, Sorbitol, Calcium carbonate.
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