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Interactions médicamenteuses

Deflazacort + Sodium polystyrene sulfonate

Gravité: Modérée

Deflazacort and Sodium polystyrene sulfonate: moderate interaction.

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Résumé

Sodium polystyrene sulfonate removes potassium through the gut and corticosteroids increase renal potassium excretion, so hypokalemia may be more pronounced. Sodium load from the resin may also add to corticosteroid-related fluid retention.

Ce que signifie cette interaction, en termes simples

Deflazacort and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Deflazacort belongs to Miscellaneous; Sodium polystyrene sulfonate belongs to Miscellaneous.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive potassium lowering through cation exchange in the colon and corticosteroid-induced kaliuresis.

Conduite à tenir

Monitor serum potassium regularly and stop or reduce the resin when potassium approaches the normal range.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Deflazacort with Sodium polystyrene sulfonate?

MediHelp rates the interaction as moderate. Deflazacort and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate removes potassium through the gut and corticosteroids increase renal potassium excretion, so hypokalemia may be more pronounced. Sodium load from the resin may also add to corticosteroid-related fluid retention.

How serious is the interaction between Deflazacort and Sodium polystyrene sulfonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium regularly and stop or reduce the resin when potassium approaches the normal range.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

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