Interactions médicamenteuses
Nevirapine + Valoctocogene roxaparvovec
Gravité: Majeure
Nevirapine and Valoctocogene roxaparvovec: major interaction.
Dernière mise à jour
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Résumé
Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
Ce que signifie cette interaction, en termes simples
Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Nevirapine belongs to Anti Virals; Valoctocogene roxaparvovec belongs to Miscellaneous.
Pourquoi elle survient
Additive hepatotoxicity; nevirapine can cause hepatocellular injury independent of the gene therapy.
Conduite à tenir
Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Nevirapine
- Elbasvir / grazoprevir + Nevirapine Contre-indiquée
- Nevirapine + Ranolazine Contre-indiquée
- Nevirapine + St john's wort Contre-indiquée
- Abemaciclib + Nevirapine Majeure
- Acalabrutinib + Nevirapine Majeure
- Amobarbital + Nevirapine Majeure
Autres interactions de Valoctocogene roxaparvovec
Questions fréquentes
Can I take Nevirapine with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
How serious is the interaction between Nevirapine and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
