Interactions médicamenteuses
Flutamide + Valoctocogene roxaparvovec
Gravité: Majeure
Flutamide and Valoctocogene roxaparvovec: major interaction.
Dernière mise à jour
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Résumé
Flutamide carries a boxed warning for hepatotoxicity, and valoctocogene roxaparvovec commonly causes transaminase elevations. Combining them may raise the risk of liver injury and complicate interpretation of liver tests.
Ce que signifie cette interaction, en termes simples
Flutamide and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Flutamide belongs to Endocrine; Valoctocogene roxaparvovec belongs to Miscellaneous.
Pourquoi elle survient
Additive hepatotoxicity from two agents that each can injure the liver.
Conduite à tenir
Avoid flutamide where possible around gene therapy; if unavoidable, monitor ALT/AST frequently and use an alternative antiandrogen with less hepatotoxic potential.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Flutamide
- Flutamide + Idelalisib Majeure
- Flutamide + Levoketoconazole Majeure
- Flutamide + Pexidartinib Majeure
- Flutamide + Pretomanid Majeure
- Apalutamide + Flutamide Modérée
- Bupivacaine implant + Flutamide Modérée
Autres interactions de Valoctocogene roxaparvovec
Questions fréquentes
Can I take Flutamide with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Flutamide and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Flutamide carries a boxed warning for hepatotoxicity, and valoctocogene roxaparvovec commonly causes transaminase elevations. Combining them may raise the risk of liver injury and complicate interpretation of liver tests.
How serious is the interaction between Flutamide and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid flutamide where possible around gene therapy; if unavoidable, monitor ALT/AST frequently and use an alternative antiandrogen with less hepatotoxic potential.
What other medicines interact with Flutamide?
MediHelp also lists interactions of Flutamide with, for example, Idelalisib, Levoketoconazole, Pexidartinib. The full list is on the Flutamide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
