Riferimento farmaci
Ephedrine
Ephedrine is a medicine in the class cardiovascular. It is used for hypotension.
- Classe del farmaco: Cardiovascular
- Indicato per: hypotension
Ultimo aggiornamento Fonti: US FDA label
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
In breve
- Classe del farmaco
- Cardiovascular
- Forme farmaceutiche comuni
- compressa, iniezione
- Dosaggi comuni
- 5 mg/ml, 12.5 mg, 25 mg
- Interazioni note
- 170 (Controindicata: 6 · Maggiore: 6 · Moderata: 88 · Minore: 70)
- Nomi commerciali
- 5
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Sympathomimetic amine that directly agonizes alpha- and beta-adrenergic receptors and indirectly causes norepinephrine release from sympathetic neurons, raising arterial pressure, cardiac output and peripheral resistance.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Clinically important hypotension in the setting of anesthesia: initial 5 mg to 10 mg IV bolus; additional boluses as needed; titrate to blood pressure goal; total not to exceed 50 mg
Gravidanza e allattamento
- Gravidanza
- Unknown Available human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; neonatal metabolic acidosis reported with maternal exposure, so monitor newborn. Animal decreased fetal survival and weight occurred with maternal toxicity.
- Allattamento
- Unknown Ephedrine is present in human milk in a single case report; effects on infant and milk production unknown. Weigh breastfeeding benefits against maternal need.
Effetti indesiderati segnalati
- Nausea
- Vomiting
- Tachycardia
- Palpitations
- Reactive hypertension
- Bradycardia
Controindicazioni
- None
Chi deve prestare attenzione
- Serious postpartum hypertension, some with stroke, reported with vasopressor plus oxytocic; monitor blood pressure carefully.
- Repeated administration can cause tachyphylaxis; have an alternative pressor ready.
- Prophylactic use to prevent hypotension is associated with increased incidence of hypertension compared with treatment of hypotension.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (170)
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
- Caffeine + Ephedrine Major
- Ephedrine + Ergotamine Major
- Ephedrine + Linezolid Major
- Ephedrine + Maprotiline Major
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per aprire la monografia completa di Ephedrine: dosi, gravidanza e allattamento, effetti indesiderati, avvertenze e tutte le interazioni.
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- IV preparation and dilution
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Domande frequenti
What is Ephedrine used for?
Ephedrine is a medicine in the class cardiovascular. It is used for Hypotension.
What side effects have been reported with Ephedrine?
Nausea, Vomiting, Tachycardia, Palpitations, Reactive hypertension, Bradycardia.
Can Ephedrine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Available human data have not identified a drug-associated risk of major birth defects, miscarriage or adverse outcomes; neonatal metabolic acidosis reported with maternal exposure, so monitor newborn. Animal decreased fetal survival and weight occurred with maternal toxicity. Breastfeeding: Unknown. Ephedrine is present in human milk in a single case report; effects on infant and milk production unknown. Weigh breastfeeding benefits against maternal need.
What does Ephedrine interact with?
MediHelp lists 170 known interactions for Ephedrine. Contraindicated: 6 · Major: 6 · Moderate: 88 · Minor: 70. The most serious include Isocarboxazid, Phenelzine, Procarbazine.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
