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Interazioni tra farmaci

Amikacin + Cefpirome

Gravità: Moderata

Amikacin and Cefpirome: moderate interaction.

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Sintesi

Concurrent cephalosporins and aminoglycosides have been associated with greater kidney injury in some reports. The effect is generally modest but may matter in patients with existing renal impairment.

Cosa significa questa interazione in parole semplici

Amikacin and Cefpirome can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amikacin belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.

Livello di evidenza: Low

Perché avviene

Possible additive nephrotoxicity.

Cosa fare

Monitor serum creatinine and amikacin concentrations, keep patients well hydrated, and adjust the amikacin dose to renal function.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Amikacin with Cefpirome?

MediHelp rates the interaction as moderate. Amikacin and Cefpirome can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent cephalosporins and aminoglycosides have been associated with greater kidney injury in some reports. The effect is generally modest but may matter in patients with existing renal impairment.

How serious is the interaction between Amikacin and Cefpirome?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin concentrations, keep patients well hydrated, and adjust the amikacin dose to renal function.

What other medicines interact with Amikacin?

MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.

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