Riferimento farmaci
Cefpirome
Cefpirome is a medicine in the class anti bacterial. It is used for febrile neutropenia.
- Classe del farmaco: Anti Bacterial
- Indicato per: febrile neutropenia
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Anti Bacterial
- Forme farmaceutiche comuni
- iniezione
- Dosaggi comuni
- 1 g, 2 g
- Interazioni note
- 45 (Moderata: 6 · Minore: 39)
- Nomi commerciali
- 2
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
Dose abituale nell'adulto (sintesi del foglio illustrativo)
1-4 g IV every 12 hours.
Gravidanza e allattamento
- Gravidanza
- Unknown No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin.
- Allattamento
- Safe Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
Effetti indesiderati segnalati
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
Chi deve prestare attenzione
- If CrCl <60 mL/min, adjust dosage to compensate for slower renal elimination rate
- Caution warranted with history of previous immediate hypersensitivity reactions to cefpirome, cephalosporins, penicillins, or other drugs
- Prescribing drug in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to patient
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (45)
- Amikacin + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
- Acetylsalicylic acid + Cefpirome Minor
- Amlodipine-hydrochlorothiazide-valsartan + Cefpirome Minor
- Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome Minor
- Atenolol-chlorthalidone + Cefpirome Minor
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Altri farmaci della stessa classe
Domande frequenti
What is Cefpirome used for?
Cefpirome is a medicine in the class anti bacterial. It is used for Febrile neutropenia, Intra-abdominal infections, Pneumonia, Skin infections, Urinary tract infections.
What side effects have been reported with Cefpirome?
Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia.
Can Cefpirome be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin. Breastfeeding: Safe. Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
What does Cefpirome interact with?
MediHelp lists 45 known interactions for Cefpirome. Moderate: 6 · Minor: 39. The most serious include Amikacin, Bupropion, Bupropion-naltrexone.
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