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Interazioni tra farmaci

Cefpirome + Streptomycin

Gravità: Moderata

Cefpirome and Streptomycin: moderate interaction.

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Sintesi

Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.

Cosa significa questa interazione in parole semplici

Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefpirome belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.

Livello di evidenza: Low

Perché avviene

Possible additive nephrotoxicity; mechanism is not well established.

Cosa fare

Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Cefpirome with Streptomycin?

MediHelp rates the interaction as moderate. Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.

How serious is the interaction between Cefpirome and Streptomycin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.

What other medicines interact with Streptomycin?

MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.

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