Interazioni tra farmaci
Atenolol + Bismuth subsalicylate
Gravità: Moderata
Atenolol and Bismuth subsalicylate: moderate interaction.
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Sintesi
Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
Cosa significa questa interazione in parole semplici
Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
Perché avviene
Salicylate inhibits prostaglandin synthesis, causing sodium and fluid retention that opposes the antihypertensive effect.
Cosa fare
Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Maggiore
- Bismuth subsalicylate + Warfarin Maggiore
- Acetylsalicylic acid + Bismuth subsalicylate Moderata
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- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderata
- Aspirin rectal + Bismuth subsalicylate Moderata
Altre interazioni di Atenolol
- Amifostine + Atenolol Maggiore
- Amiodarone + Atenolol Maggiore
- Atenolol + Atenolol-chlorthalidone Maggiore
- Atenolol + Betaxolol Maggiore
- Atenolol + Bisoprolol Maggiore
- Atenolol + Carvedilol Maggiore
Domande frequenti
Can I take Atenolol with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
How serious is the interaction between Atenolol and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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