Riferimento farmaci
Bismuth subsalicylate
Bismuth subsalicylate is a medicine in the class gastrointestinal tract. It is used for diarrhea.
- Classe del farmaco: Gastrointestinal Tract
- Indicato per: diarrhea
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Gastrointestinal Tract
- Forme farmaceutiche comuni
- compressa, soluzione, sospensione orale, capsula, polvere
- Dosaggi comuni
- 262 mg, 525 mg/30 ml, 525 mg/15 ml
- Interazioni note
- 35 (Maggiore: 2 · Moderata: 24 · Minore: 9)
- Nomi commerciali
- 133
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Antimicrobial, anti-inflammatory action (bismuth); antisecretory effect (salicylate).
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Diarrhea, Gas, Upset Stomach, Indigestion, Heartburn, Nausea:2 tablets (262 mg/tab) or 30 mL every hour; maximum daily dose: 8 regular-strength doses or 4 extra-strength doses.
Gravidanza e allattamento
- Gravidanza
- Unsafe The salicylate part is absorbed and acts like aspirin: risk of fetal kidney problems, low amniotic fluid and ductus closure later in pregnancy, and bleeding near term. Avoid in pregnancy; use oral rehydration and, if needed, loperamide.
- Allattamento
- Unsafe No direct data; salicylate may pass to the infant through milk. LactMed prefers alternatives. Avoid; use rehydration or loperamide if needed.
Effetti indesiderati segnalati
- Diarrhea
- Nausea
- Abdominal pain
- Melena
Controindicazioni
- Hypersensitivity to bismuth, aspirin, other salicylates
- Infectious diarrhea, high fever, von Willebrand disease, hemorrhage, ulcer or GI bleeding with black or bloody stool, hemophilia
- In pediatric patients, chicken pox or influenza (risk of Reye syndrome)
Chi deve prestare attenzione
- Bismuth subcitrate potassium may cause temporary and harmless darkening of tongue and/or black stools, generally reversible within several days after treatment stopped.
- Bismuth absorbs x-rays and may interfere with x-ray diagnostic procedures of gastrointestinal tract.
- Not to be administered to children or teenagers recovering from flu-like symptoms or chickenpox; increased incidence of Reye syndrome, associated with salicylate products
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (35)
- Bismuth subsalicylate + Dichlorphenamide Major
- Bismuth subsalicylate + Warfarin Major
- Acetylsalicylic acid + Bismuth subsalicylate Moderate
- Amlodipine-benazepril + Bismuth subsalicylate Moderate
- Aspirin + Bismuth subsalicylate Moderate
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderate
- Aspirin rectal + Bismuth subsalicylate Moderate
- Atenolol + Bismuth subsalicylate Moderate
- Benazepril + Bismuth subsalicylate Moderate
- Betaxolol + Bismuth subsalicylate Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Bismuth subsalicylate used for?
Bismuth subsalicylate is a medicine in the class gastrointestinal tract. It is used for Diarrhea, Helicobacter pylori bacteria, Indigestion, Traveler's diarrhea.
What side effects have been reported with Bismuth subsalicylate?
Diarrhea, Nausea, Abdominal pain, Melena.
Can Bismuth subsalicylate be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. The salicylate part is absorbed and acts like aspirin: risk of fetal kidney problems, low amniotic fluid and ductus closure later in pregnancy, and bleeding near term. Avoid in pregnancy; use oral rehydration and, if needed, loperamide. Breastfeeding: Unsafe. No direct data; salicylate may pass to the infant through milk. LactMed prefers alternatives. Avoid; use rehydration or loperamide if needed.
What does Bismuth subsalicylate interact with?
MediHelp lists 35 known interactions for Bismuth subsalicylate. Major: 2 · Moderate: 24 · Minor: 9. The most serious include Dichlorphenamide, Warfarin, Acetylsalicylic acid.
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