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Interazioni tra farmaci

Benzphetamine + Isocarboxazid

Gravità: Controindicata

Benzphetamine and Isocarboxazid: contraindicated interaction.

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Sintesi

Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.

Cosa significa questa interazione in parole semplici

Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: High

Perché avviene

MAO inhibition leaves norepinephrine stores increased, and the amphetamine-like release of these stores causes an exaggerated pressor response.

Cosa fare

Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Benzphetamine with Isocarboxazid?

MediHelp rates the interaction as contraindicated. Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.

How serious is the interaction between Benzphetamine and Isocarboxazid?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.

What other medicines interact with Isocarboxazid?

MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.

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