Interazioni tra farmaci
Cefadroxil + Plazomicin
Gravità: Moderata
Cefadroxil and Plazomicin: moderate interaction.
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Sintesi
Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
Cosa significa questa interazione in parole semplici
Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefadroxil belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Perché avviene
Additive nephrotoxicity with reduced renal clearance of both drugs as kidney function declines.
Cosa fare
Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefadroxil
- Amikacin + Cefadroxil Moderata
- Avelumab + Cefadroxil Moderata
- Balstilimab + Cefadroxil Moderata
- Bcg vaccine live + Cefadroxil Moderata
- Cefadroxil + Cholera vaccine Moderata
- Cefadroxil + Gentamicin Moderata
Altre interazioni di Plazomicin
- Cefaclor + Plazomicin Moderata
- Cefalexin + Plazomicin Moderata
- Cefazolin + Plazomicin Moderata
- Cefditoren + Plazomicin Moderata
- Cefepime + Plazomicin Moderata
- Cefixime + Plazomicin Moderata
Domande frequenti
Can I take Cefadroxil with Plazomicin?
MediHelp rates the interaction as moderate. Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
How serious is the interaction between Cefadroxil and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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