Interazioni tra farmaci
Cefalexin + Plazomicin
Gravità: Moderata
Cefalexin and Plazomicin: moderate interaction.
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Sintesi
Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
Cosa significa questa interazione in parole semplici
Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefalexin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Perché avviene
Additive nephrotoxic potential, with reduced renal clearance increasing aminoglycoside accumulation and ototoxicity.
Cosa fare
Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefalexin
- Amikacin + Cefalexin Moderata
- Avelumab + Cefalexin Moderata
- Balstilimab + Cefalexin Moderata
- Bcg vaccine live + Cefalexin Moderata
- Cefalexin + Cholera vaccine Moderata
- Cefalexin + Gentamicin Moderata
Altre interazioni di Plazomicin
- Cefaclor + Plazomicin Moderata
- Cefadroxil + Plazomicin Moderata
- Cefazolin + Plazomicin Moderata
- Cefditoren + Plazomicin Moderata
- Cefepime + Plazomicin Moderata
- Cefixime + Plazomicin Moderata
Domande frequenti
Can I take Cefalexin with Plazomicin?
MediHelp rates the interaction as moderate. Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
How serious is the interaction between Cefalexin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
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