Interazioni tra farmaci
Cyclosporin + Ixekizumab
Gravità: Minore
Cyclosporin and Ixekizumab: minor interaction.
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Sintesi
Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
Cosa significa questa interazione in parole semplici
Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Ixekizumab belongs to Miscellaneous.
Perché avviene
Cytokine normalization may modestly increase CYP-mediated cyclosporine metabolism; this is theoretical.
Cosa fare
Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
Cosa chiedere al farmacista
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Altre interazioni di Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Controindicata
- Aliskiren + Cyclosporin Controindicata
- Bcg vaccine live + Cyclosporin Controindicata
- Bosentan + Cyclosporin Controindicata
- Cidofovir + Cyclosporin Controindicata
- Cyclosporin + Dengue vaccine Controindicata
Altre interazioni di Ixekizumab
- Ixekizumab + Measles mumps and rubella vaccine Maggiore
- Ixekizumab + Upadacitinib Maggiore
- Ifosfamide + Ixekizumab Moderata
- Ixekizumab + Lomustine Moderata
- Carbamazepine + Ixekizumab Minore
- Ethosuximide + Ixekizumab Minore
Domande frequenti
Can I take Cyclosporin with Ixekizumab?
MediHelp rates the interaction as minor. Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
How serious is the interaction between Cyclosporin and Ixekizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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