Interazioni tra farmaci
Delafloxacin + Zinc
Gravità: Moderata
Delafloxacin and Zinc: moderate interaction.
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Sintesi
Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
Cosa significa questa interazione in parole semplici
Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.
Perché avviene
Chelation of delafloxacin by polyvalent metal cations reduces gastrointestinal absorption.
Cosa fare
Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderata
- Calcium carbonate + Delafloxacin Moderata
- Calcium + Delafloxacin Moderata
- Carbonyl iron + Delafloxacin Moderata
- Delafloxacin + Didanosine Moderata
- Delafloxacin + Ferrous fumarate Moderata
Altre interazioni di Zinc
- Alendronate + Zinc Moderata
- Baloxavir marboxil + Zinc Moderata
- Cefalexin + Zinc Moderata
- Ciprofloxacin + Zinc Moderata
- Dolutegravir + Zinc Moderata
- Doxycycline + Zinc Moderata
Domande frequenti
Can I take Delafloxacin with Zinc?
MediHelp rates the interaction as moderate. Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Delafloxacin and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
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