Interazioni tra farmaci
Dihydroergotamine + Voriconazole
Gravità: Controindicata
Dihydroergotamine and Voriconazole: contraindicated interaction.
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Sintesi
Voriconazole raises dihydroergotamine levels and risks ergotism, with severe peripheral and cerebral vasospasm and ischemia. The outcome can be limb or organ threatening.
Cosa significa questa interazione in parole semplici
Dihydroergotamine and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Voriconazole belongs to Anti Fungals.
Perché avviene
Strong CYP3A4 inhibition by voriconazole reduces dihydroergotamine metabolism.
Cosa fare
Do not use together; choose a non-ergot migraine therapy during voriconazole treatment.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Voriconazole
- Avanafil + Voriconazole Controindicata
- Butabarbital + Voriconazole Controindicata
- Carbamazepine + Voriconazole Controindicata
- Conivaptan + Voriconazole Controindicata
- Dihydroergotamine intranasal + Voriconazole Controindicata
- Dofetilide + Voriconazole Controindicata
Altre interazioni di Dihydroergotamine
- Almotriptan + Dihydroergotamine Controindicata
- Clarithromycin + Dihydroergotamine Controindicata
- Dihydroergotamine + Dopamine Controindicata
- Dihydroergotamine + Dronedarone Controindicata
- Dihydroergotamine + Efavirenz Controindicata
- Dihydroergotamine + Eletriptan Controindicata
Domande frequenti
Can I take Dihydroergotamine with Voriconazole?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Voriconazole raises dihydroergotamine levels and risks ergotism, with severe peripheral and cerebral vasospasm and ischemia. The outcome can be limb or organ threatening.
How serious is the interaction between Dihydroergotamine and Voriconazole?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a non-ergot migraine therapy during voriconazole treatment.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
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