Interazioni tra farmaci
Dronedarone + Hydroxychloroquine
Gravità: Controindicata
Dronedarone and Hydroxychloroquine: contraindicated interaction.
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Sintesi
Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
Cosa significa questa interazione in parole semplici
Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dronedarone belongs to Cardiovascular; Hydroxychloroquine belongs to Musculoskeletal.
Perché avviene
Additive delayed ventricular repolarization through potassium channel blockade.
Cosa fare
Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Controindicata
- Cisapride + Hydroxychloroquine Controindicata
- Hydroxychloroquine + Pimozide Controindicata
- Hydroxychloroquine + Thioridazine Controindicata
- Hydroxychloroquine + Vandetanib Controindicata
- Adagrasib + Hydroxychloroquine Maggiore
Altre interazioni di Dronedarone
- Adagrasib + Dronedarone Controindicata
- Amiodarone + Dronedarone Controindicata
- Arsenic trioxide + Dronedarone Controindicata
- Artemether / lumefantrine + Dronedarone Controindicata
- Atazanavir + Dronedarone Controindicata
- Azithromycin + Dronedarone Controindicata
Domande frequenti
Can I take Dronedarone with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
How serious is the interaction between Dronedarone and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Pimozide. The full list is on the Hydroxychloroquine page.
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