Interazioni tra farmaci
Cisapride + Hydroxychloroquine
Gravità: Controindicata
Cisapride and Hydroxychloroquine: contraindicated interaction.
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Sintesi
Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
Cosa significa questa interazione in parole semplici
Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cisapride belongs to Gastrointestinal Tract; Hydroxychloroquine belongs to Musculoskeletal.
Perché avviene
Additive inhibition of cardiac potassium channels with QT prolongation.
Cosa fare
Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Cisapride
- Apomorphine + Cisapride Controindicata
- Artemether + Cisapride Controindicata
- Azithromycin + Cisapride Controindicata
- Ceritinib + Cisapride Controindicata
- Chloroquine + Cisapride Controindicata
- Cisapride + Citalopram Controindicata
Altre interazioni di Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Controindicata
- Dronedarone + Hydroxychloroquine Controindicata
- Hydroxychloroquine + Pimozide Controindicata
- Hydroxychloroquine + Thioridazine Controindicata
- Hydroxychloroquine + Vandetanib Controindicata
- Adagrasib + Hydroxychloroquine Maggiore
Domande frequenti
Can I take Cisapride with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
How serious is the interaction between Cisapride and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
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