Interazioni tra farmaci
Eletriptan + Erythromycin lactobionate
Gravità: Controindicata
Eletriptan and Erythromycin lactobionate: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Intravenous erythromycin inhibits CYP3A4 and substantially increases eletriptan concentrations and half-life. The result may be exaggerated vasoconstriction with cardiovascular and hypertensive risk.
Cosa significa questa interazione in parole semplici
Eletriptan and Erythromycin lactobionate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eletriptan belongs to Central Nervous System; Erythromycin lactobionate belongs to Anti Bacterial.
Perché avviene
Inhibition of CYP3A4-mediated metabolism of eletriptan.
Cosa fare
Do not use eletriptan within 72 hours of erythromycin. Consider another antibiotic such as azithromycin or another triptan.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Eletriptan e Erythromycin lactobionate, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Eletriptan
- Almotriptan + Eletriptan Controindicata
- Atazanavir + Eletriptan Controindicata
- Ceritinib + Eletriptan Controindicata
- Clarithromycin + Eletriptan Controindicata
- Cobicistat + Eletriptan Controindicata
- Conivaptan + Eletriptan Controindicata
Altre interazioni di Erythromycin lactobionate
- Cisapride + Erythromycin lactobionate Controindicata
- Dihydroergotamine + Erythromycin lactobionate Controindicata
- Dronedarone + Erythromycin lactobionate Controindicata
- Ergotamine + Erythromycin lactobionate Controindicata
- Erythromycin lactobionate + Flibanserin Controindicata
- Erythromycin lactobionate + Lovastatin Controindicata
Domande frequenti
Can I take Eletriptan with Erythromycin lactobionate?
MediHelp rates the interaction as contraindicated. Eletriptan and Erythromycin lactobionate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intravenous erythromycin inhibits CYP3A4 and substantially increases eletriptan concentrations and half-life. The result may be exaggerated vasoconstriction with cardiovascular and hypertensive risk.
How serious is the interaction between Eletriptan and Erythromycin lactobionate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use eletriptan within 72 hours of erythromycin. Consider another antibiotic such as azithromycin or another triptan.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
