Interazioni tra farmaci
Ergotamine + Sumatriptan
Gravità: Controindicata
Ergotamine and Sumatriptan: contraindicated interaction.
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Sintesi
Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
Cosa significa questa interazione in parole semplici
Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ergotamine belongs to Central Nervous System; Sumatriptan belongs to Central Nervous System.
Perché avviene
Additive vasoconstriction through serotonin receptors
Cosa fare
Do not administer within 24 hours of each other.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Sumatriptan
- Almotriptan + Sumatriptan Controindicata
- Dihydroergotamine intranasal + Sumatriptan Controindicata
- Dihydroergotamine + Sumatriptan Controindicata
- Eletriptan + Sumatriptan Controindicata
- Ergoloid mesylates + Sumatriptan Controindicata
- Frovatriptan + Sumatriptan Controindicata
Altre interazioni di Ergotamine
- Almotriptan + Ergotamine Controindicata
- Atazanavir + Ergotamine Controindicata
- Clarithromycin + Ergotamine Controindicata
- Cobicistat + Ergotamine Controindicata
- Darunavir + Ergotamine Controindicata
- Dihydroergotamine intranasal + Ergotamine Controindicata
Domande frequenti
Can I take Ergotamine with Sumatriptan?
MediHelp rates the interaction as contraindicated. Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
How serious is the interaction between Ergotamine and Sumatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.
What other medicines interact with Sumatriptan?
MediHelp also lists interactions of Sumatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Sumatriptan page.
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