Interazioni tra farmaci
Folic acid + Pafolacianine
Gravità: Moderata
Folic acid and Pafolacianine: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
Cosa significa questa interazione in parole semplici
Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Competitive binding at folate receptors reduces pafolacianine uptake.
Cosa fare
Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Folic acid e Pafolacianine, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 7 giorni sul web. Nessuna carta.
Altre interazioni di Folic acid
- Ethotoin + Folic acid Moderata
- Folic acid + Fosphenytoin Moderata
- Folic acid + Glucarpidase Moderata
- Folic acid + Methotrexate Moderata
- Folic acid + Phenobarbital Moderata
- Folic acid + Phenytoin Moderata
Domande frequenti
Can I take Folic acid with Pafolacianine?
MediHelp rates the interaction as moderate. Folic acid and Pafolacianine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pafolacianine is an optical imaging agent that targets folate receptors on ovarian cancer cells. Folic acid competes for these receptors and may reduce tumor uptake, causing lesions to be missed during surgery.
How serious is the interaction between Folic acid and Pafolacianine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold folic acid and folate-containing supplements for at least 48 hours before pafolacianine administration.
What other medicines interact with Folic acid?
MediHelp also lists interactions of Folic acid with, for example, Ethotoin, Fosphenytoin, Glucarpidase. The full list is on the Folic acid page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
