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Interazioni tra farmaci

Griseofulvin + Verteporfin

Gravità: Moderata

Griseofulvin and Verteporfin: moderate interaction.

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Sintesi

Griseofulvin is a photosensitizing drug, and taking it with verteporfin may further increase the risk of skin photosensitivity reactions after verteporfin therapy.

Cosa significa questa interazione in parole semplici

Griseofulvin and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Griseofulvin belongs to Anti Fungals; Verteporfin belongs to Miscellaneous.

Livello di evidenza: Low

Perché avviene

Additive phototoxic potential from two photosensitizing agents.

Cosa fare

Counsel patients to rigorously avoid sunlight and bright indoor light on skin and eyes for the period advised after verteporfin infusion. Consider deferring griseofulvin where practical.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Griseofulvin with Verteporfin?

MediHelp rates the interaction as moderate. Griseofulvin and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Griseofulvin is a photosensitizing drug, and taking it with verteporfin may further increase the risk of skin photosensitivity reactions after verteporfin therapy.

How serious is the interaction between Griseofulvin and Verteporfin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to rigorously avoid sunlight and bright indoor light on skin and eyes for the period advised after verteporfin infusion. Consider deferring griseofulvin where practical.

What other medicines interact with Verteporfin?

MediHelp also lists interactions of Verteporfin with, for example, Doxycycline, Minocycline, Tetracycline. The full list is on the Verteporfin page.

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