Drug interactions
Griseofulvin + Verteporfin
Severity: Moderate
Griseofulvin and Verteporfin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a photosensitizing drug, and taking it with verteporfin may further increase the risk of skin photosensitivity reactions after verteporfin therapy.
What this interaction means in plain words
Griseofulvin and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Griseofulvin belongs to Anti Fungals; Verteporfin belongs to Miscellaneous.
Why it happens
Additive phototoxic potential from two photosensitizing agents.
What to do
Counsel patients to rigorously avoid sunlight and bright indoor light on skin and eyes for the period advised after verteporfin infusion. Consider deferring griseofulvin where practical.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Verteporfin
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Verteporfin?
MediHelp rates the interaction as moderate. Griseofulvin and Verteporfin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Griseofulvin is a photosensitizing drug, and taking it with verteporfin may further increase the risk of skin photosensitivity reactions after verteporfin therapy.
How serious is the interaction between Griseofulvin and Verteporfin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to rigorously avoid sunlight and bright indoor light on skin and eyes for the period advised after verteporfin infusion. Consider deferring griseofulvin where practical.
What other medicines interact with Verteporfin?
MediHelp also lists interactions of Verteporfin with, for example, Doxycycline, Minocycline, Tetracycline. The full list is on the Verteporfin page.
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