Interazioni tra farmaci
Ifosfamide + Talimogene laherparepvec
Gravità: Controindicata
Ifosfamide and Talimogene laherparepvec: contraindicated interaction.
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Sintesi
Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
Cosa significa questa interazione in parole semplici
Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Talimogene laherparepvec belongs to Oncology.
Perché avviene
Immunosuppression from chemotherapy impairs control of the replicating oncolytic herpes virus.
Cosa fare
Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Controindicata
- Ifosfamide + Measles mumps and rubella vaccine Controindicata
- Ifosfamide + Measles mumps and rubella vaccine live Controindicata
- Ifosfamide + Measles mumps rubella and varicella vaccine live Controindicata
- Ifosfamide + Measles vaccine Controindicata
- Ifosfamide + Rotavirus oral vaccine live Controindicata
Altre interazioni di Talimogene laherparepvec
Domande frequenti
Can I take Ifosfamide with Talimogene laherparepvec?
MediHelp rates the interaction as contraindicated. Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
How serious is the interaction between Ifosfamide and Talimogene laherparepvec?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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