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Interazioni tra farmaci

Leflunomide + Measles mumps and rubella vaccine live

Gravità: Controindicata

Leflunomide and Measles mumps and rubella vaccine live: contraindicated interaction.

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Sintesi

This live attenuated vaccine may cause disseminated infection in a patient immunosuppressed by leflunomide. The immune response may also be inadequate.

Cosa significa questa interazione in parole semplici

Leflunomide and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Moderate

Perché avviene

Impaired lymphocyte function reduces control of live attenuated virus replication.

Cosa fare

Avoid during leflunomide therapy and until washout is confirmed; give before treatment starts.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Leflunomide with Measles mumps and rubella vaccine live?

MediHelp rates the interaction as contraindicated. Leflunomide and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated vaccine may cause disseminated infection in a patient immunosuppressed by leflunomide. The immune response may also be inadequate.

How serious is the interaction between Leflunomide and Measles mumps and rubella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during leflunomide therapy and until washout is confirmed; give before treatment starts.

What other medicines interact with Leflunomide?

MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps rubella and varicella vaccine live. The full list is on the Leflunomide page.

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