Interazioni tra farmaci
Leflunomide + Measles vaccine
Gravità: Controindicata
Leflunomide and Measles vaccine: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
Cosa significa questa interazione in parole semplici
Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Impaired lymphocyte function reduces control of live attenuated virus replication.
Cosa fare
Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Leflunomide
- Bcg vaccine live + Leflunomide Controindicata
- Influenza virus vaccine quadrivalent intranasal + Leflunomide Controindicata
- Leflunomide + Measles mumps and rubella vaccine live Controindicata
- Leflunomide + Measles mumps rubella and varicella vaccine live Controindicata
- Leflunomide + Smallpox vaccine live Controindicata
- Alefacept + Leflunomide Maggiore
Domande frequenti
Can I take Leflunomide with Measles vaccine?
MediHelp rates the interaction as contraindicated. Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
How serious is the interaction between Leflunomide and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
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