医薬品リファレンス
Pramoxine
Pramoxine is a medicine in the class central nervous system. It is used for burns.
- 薬効分類: Central Nervous System
- 効能・効果: burns
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- ローション剤, 溶液, クリーム剤, スプレー剤, 吸入器
- 一般的な規格
- 10 mg/ml, 1 g/100 ml, 1 g/100 g
- 商品名
- 21
- 国・市場
- 1
何に使われるか
作用のしくみ
Pramoxine is a topical local anaesthetic (a morpholine ether, chemically distinct from the ester and amide anaesthetics). It stabilises the neuronal membrane by blocking voltage-gated sodium channels. This reversibly inhibits the initiation and conduction of nerve impulses in sensory nerve endings in the skin.
成人の通常用量（添付文書の要約）
Pain and itching from insect bites, minor burns, sunburn, minor skin irritations, cuts, scrapes, poison ivy/oak/sumac rashes: apply to affected area, topical, not more than 3 to 4 times daily (adults and children 2 years and older)
妊娠と授乳
- 妊娠
- Safe Topical anaesthetic in anti-itch and haemorrhoid creams. Little is absorbed through the skin, so fetal exposure is expected to be minimal. Short use on small areas is acceptable; OTC labels: ask a health professional first.
- 授乳
- Safe No milk data; skin use gives little absorption. Swallowing it mainly causes nausea and vomiting without serious toxicity (LactMed). If applied to the breast or nipple, wipe it off thoroughly before feeding.
報告されている副作用
- Burning at application site
- Stinging at application site
- Local skin irritation
- Redness (erythema)
- Itching or worsening of pruritus
- Skin dryness
禁忌
- Do not use in the eyes or nose, or over large areas of the body for prolonged periods.
注意が必要な方
- For external use only. Do not use in the eyes or nose, over large areas of the body, or for prolonged periods.
- Ask a doctor before use on chicken pox or measles.
- Stop use and ask a doctor if condition worsens, symptoms last more than 7 days, or clear up and occur again within a few days.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Pramoxineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
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同じ分類のほかの薬剤
よくある質問
What is Pramoxine used for?
Pramoxine is a medicine in the class central nervous system. It is used for Burns, Insect bites, Pruritus.
What side effects have been reported with Pramoxine?
Burning at application site, Stinging at application site, Local skin irritation, Redness (erythema), Itching or worsening of pruritus, Skin dryness.
Can Pramoxine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Topical anaesthetic in anti-itch and haemorrhoid creams. Little is absorbed through the skin, so fetal exposure is expected to be minimal. Short use on small areas is acceptable; OTC labels: ask a health professional first. Breastfeeding: Safe. No milk data; skin use gives little absorption. Swallowing it mainly causes nausea and vomiting without serious toxicity (LactMed). If applied to the breast or nipple, wipe it off thoroughly before feeding.
What does Pramoxine interact with?
MediHelp does not list a checked interaction for Pramoxine yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
