相互作用
Adenovirus types 4 and 7 live + Certolizumab pegol
重症度: 併用禁忌
Adenovirus types 4 and 7 live and Certolizumab pegol: contraindicated interaction.
最終更新日
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概要
The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.
この相互作用をわかりやすく説明すると
Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
TNF inhibition impairs immune control of live attenuated virus, raising infection risk and reducing vaccine response.
対処法
Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Adenovirus types 4 and 7 liveとCertolizumab pegolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Certolizumab pegolのその他の相互作用
- Bcg intravesical live + Certolizumab pegol 併用禁忌
- Bcg vaccine live + Certolizumab pegol 併用禁忌
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine live 併用禁忌
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live 併用禁忌
よくある質問
Can I take Adenovirus types 4 and 7 live with Certolizumab pegol?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.
How serious is the interaction between Adenovirus types 4 and 7 live and Certolizumab pegol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Bcg intravesical live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Certolizumab pegol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。