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相互作用

Certolizumab pegol + Measles mumps and rubella vaccine live

重症度: 併用禁忌

Certolizumab pegol and Measles mumps and rubella vaccine live: contraindicated interaction.

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概要

MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.

この相互作用をわかりやすく説明すると

Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

エビデンスレベル: Moderate

なぜ起こるのか

TNF inhibition impairs immune control of live attenuated viruses.

対処法

Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Certolizumab pegolとMeasles mumps and rubella vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Certolizumab pegol with Measles mumps and rubella vaccine live?

MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.

How serious is the interaction between Certolizumab pegol and Measles mumps and rubella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.

What other medicines interact with Certolizumab pegol?

MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.

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MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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