相互作用
Bcg intravesical live + Certolizumab pegol
重症度: 併用禁忌
Bcg intravesical live and Certolizumab pegol: contraindicated interaction.
最終更新日
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概要
Intravesical BCG is live Mycobacterium bovis. In patients on a TNF inhibitor, impaired granulomatous immunity may permit systemic BCG infection (BCGosis), and the antitumor response may be reduced.
この相互作用をわかりやすく説明すると
Bcg intravesical live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
TNF is essential for granuloma formation and mycobacterial containment, so its inhibition allows BCG dissemination.
対処法
Avoid intravesical BCG during certolizumab therapy and consider alternative bladder cancer treatment. If BCG is essential, discuss pausing certolizumab with the treating specialists.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg intravesical liveとCertolizumab pegolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Certolizumab pegolのその他の相互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 併用禁忌
- Bcg vaccine live + Certolizumab pegol 併用禁忌
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine 併用禁忌
- Certolizumab pegol + Measles mumps and rubella vaccine live 併用禁忌
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live 併用禁忌
よくある質問
Can I take Bcg intravesical live with Certolizumab pegol?
MediHelp rates the interaction as contraindicated. Bcg intravesical live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intravesical BCG is live Mycobacterium bovis. In patients on a TNF inhibitor, impaired granulomatous immunity may permit systemic BCG infection (BCGosis), and the antitumor response may be reduced.
How serious is the interaction between Bcg intravesical live and Certolizumab pegol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid intravesical BCG during certolizumab therapy and consider alternative bladder cancer treatment. If BCG is essential, discuss pausing certolizumab with the treating specialists.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Certolizumab pegol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
