相互作用
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin
重症度: 重大
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin: major interaction.
最終更新日
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概要
Topical antibiotics applied to a wound can degrade or damage the living cultured cell construct. This may reduce the graft's viability and therapeutic effect.
この相互作用をわかりやすく説明すると
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Direct cytotoxic effect of topical antibiotics on the cultured cells at the wound site.
対処法
Do not apply the antibiotic ointment to the site before the graft. If exposed, irrigate the wound thoroughly with saline and allow a washout period before application.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Allogeneic cultured keratinocytes / fibroblasts in bovine collagenとBacitracin-neomycin-polymyxinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bacitracin-neomycin-polymyxinのその他の相互作用
よくある質問
Can I take Allogeneic cultured keratinocytes / fibroblasts in bovine collagen with Bacitracin-neomycin-polymyxin?
MediHelp rates the interaction as major. Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Topical antibiotics applied to a wound can degrade or damage the living cultured cell construct. This may reduce the graft's viability and therapeutic effect.
How serious is the interaction between Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not apply the antibiotic ointment to the site before the graft. If exposed, irrigate the wound thoroughly with saline and allow a washout period before application.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Atracurium, Capreomycin, Cidofovir. The full list is on the Bacitracin-neomycin-polymyxin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
