相互作用
Bacitracin-neomycin-polymyxin + Capreomycin
重症度: 重大
Bacitracin-neomycin-polymyxin and Capreomycin: major interaction.
最終更新日
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概要
Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
この相互作用をわかりやすく説明すると
Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive nephrotoxicity, ototoxicity and neuromuscular blockade from drugs with overlapping toxicity.
対処法
Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bacitracin-neomycin-polymyxinとCapreomycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bacitracin-neomycin-polymyxinのその他の相互作用
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin 重大
- Atracurium + Bacitracin-neomycin-polymyxin 重大
- Bacitracin-neomycin-polymyxin + Cidofovir 重大
- Bacitracin-neomycin-polymyxin + Cisatracurium 重大
- Bacitracin-neomycin-polymyxin + Pancuronium 重大
- Bacitracin-neomycin-polymyxin + Rocuronium 重大
よくある質問
Can I take Bacitracin-neomycin-polymyxin with Capreomycin?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Capreomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Cidofovir. The full list is on the Bacitracin-neomycin-polymyxin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
