相互作用
Amikacin + Cefoxitin
重症度: 中等度
Amikacin and Cefoxitin: moderate interaction.
最終更新日
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概要
Amikacin is nephrotoxic and ototoxic, and concurrent cephalosporins have been linked in some reports with additional kidney injury. Reduced renal function increases aminoglycoside accumulation and the risk of hearing damage.
この相互作用をわかりやすく説明すると
Amikacin and Cefoxitin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefoxitin belongs to Anti Bacterial.
なぜ起こるのか
Additive nephrotoxicity, with decreased renal clearance raising aminoglycoside exposure.
対処法
Monitor serum creatinine and amikacin levels, and ask about hearing or balance symptoms. Adjust the amikacin dose to renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmikacinとCefoxitinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefoxitinのその他の相互作用
Amikacinのその他の相互作用
よくある質問
Can I take Amikacin with Cefoxitin?
MediHelp rates the interaction as moderate. Amikacin and Cefoxitin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amikacin is nephrotoxic and ototoxic, and concurrent cephalosporins have been linked in some reports with additional kidney injury. Reduced renal function increases aminoglycoside accumulation and the risk of hearing damage.
How serious is the interaction between Amikacin and Cefoxitin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels, and ask about hearing or balance symptoms. Adjust the amikacin dose to renal function.
What other medicines interact with Cefoxitin?
MediHelp also lists interactions of Cefoxitin with, for example, Aztreonam, Bcg vaccine live, Chloramphenicol. The full list is on the Cefoxitin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
