相互作用
Amlodipine-atorvastatin + Calcium gluconate
重症度: 中等度
Amlodipine-atorvastatin and Calcium gluconate: moderate interaction.
最終更新日
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概要
Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
この相互作用をわかりやすく説明すると
Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
なぜ起こるのか
Raised extracellular calcium competitively overcomes calcium channel blockade by amlodipine.
対処法
Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Amlodipine-atorvastatinとCalcium gluconateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amlodipine-atorvastatinのその他の相互作用
Calcium gluconateのその他の相互作用
よくある質問
Can I take Amlodipine-atorvastatin with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
How serious is the interaction between Amlodipine-atorvastatin and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
