相互作用
Calcium gluconate + Ceftriaxone
重症度: 併用禁忌
Calcium gluconate and Ceftriaxone: contraindicated interaction.
最終更新日
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概要
Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
この相互作用をわかりやすく説明すると
Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Calcium gluconate belongs to Gastrointestinal Tract; Ceftriaxone belongs to Anti Bacterial.
なぜ起こるのか
Ceftriaxone binds calcium to form poorly soluble ceftriaxone-calcium precipitate.
対処法
Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、Calcium gluconateとCeftriaxoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ceftriaxoneのその他の相互作用
Calcium gluconateのその他の相互作用
よくある質問
Can I take Calcium gluconate with Ceftriaxone?
MediHelp rates the interaction as contraindicated. Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
How serious is the interaction between Calcium gluconate and Ceftriaxone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium chloride, Calcium, Lactated ringer's. The full list is on the Ceftriaxone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
