相互作用
Amobarbital + Ethinyl estradiol-norgestimate
重症度: 重大
Amobarbital and Ethinyl estradiol-norgestimate: major interaction.
最終更新日
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概要
Barbiturates induce hepatic enzymes and can lower circulating ethinyl estradiol and progestin levels. Contraceptive failure is possible.
この相互作用をわかりやすく説明すると
Amobarbital and Ethinyl estradiol-norgestimate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amobarbital belongs to Central Nervous System; Ethinyl estradiol-norgestimate belongs to Endocrine.
なぜ起こるのか
Induction of CYP3A4 and other hepatic enzymes accelerates hormone metabolism.
対処法
Use a non-hormonal contraceptive method during barbiturate use and for several weeks after stopping. Do not rely on combined pills alone.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmobarbitalとEthinyl estradiol-norgestimateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ethinyl estradiol-norgestimateのその他の相互作用
- Ethinyl estradiol-norgestimate + Fezolinetant 併用禁忌
- Ethinyl estradiol-norgestimate + Ombitasvir / paritaprevir / ritonavir and dasabuvir 併用禁忌
- Ethinyl estradiol-norgestimate + Tranexamic acid 併用禁忌
- Aminocaproic acid + Ethinyl estradiol-norgestimate 重大
- Anastrozole + Ethinyl estradiol-norgestimate 重大
- Apalutamide + Ethinyl estradiol-norgestimate 重大
Amobarbitalのその他の相互作用
よくある質問
Can I take Amobarbital with Ethinyl estradiol-norgestimate?
MediHelp rates the interaction as major. Amobarbital and Ethinyl estradiol-norgestimate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Barbiturates induce hepatic enzymes and can lower circulating ethinyl estradiol and progestin levels. Contraceptive failure is possible.
How serious is the interaction between Amobarbital and Ethinyl estradiol-norgestimate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a non-hormonal contraceptive method during barbiturate use and for several weeks after stopping. Do not rely on combined pills alone.
What other medicines interact with Ethinyl estradiol-norgestimate?
MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
