本文へスキップ

相互作用

Amoxicillin-clavulanic acid + Omadacycline

重症度: 中等度

Amoxicillin-clavulanic acid and Omadacycline: moderate interaction.

最終更新日

医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。

このページの臨床コンテンツは英語でのみ提供されています。

概要

Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.

この相互作用をわかりやすく説明すると

Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amoxicillin-clavulanic acid belongs to Anti Bacterial; Omadacycline belongs to Anti Bacterial.

エビデンスレベル: Low

なぜ起こるのか

Pharmacodynamic antagonism: inhibition of bacterial growth reduces the activity of beta-lactams that act on dividing cells.

対処法

Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

ページ全体を見る

アカウントを作成してPro+トライアルを始めると、Amoxicillin-clavulanic acidとOmadacyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

WebでPro+を14日間無料でお試し。カード登録不要。

よくある質問

Can I take Amoxicillin-clavulanic acid with Omadacycline?

MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Omadacycline is a bacteriostatic tetracycline that may theoretically blunt penicillin bactericidal effects. There is limited clinical evidence of harm. Relevance is greatest in serious infections.

How serious is the interaction between Amoxicillin-clavulanic acid and Omadacycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining for severe infections unless dual therapy is clearly justified. Monitor clinical response if used together.

What other medicines interact with Amoxicillin-clavulanic acid?

MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

A–Zで探す · 相互作用

アプリを入手 ログイン