相互作用
Omadacycline + Tretinoin
重症度: 重大
Omadacycline and Tretinoin: major interaction.
最終更新日
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概要
Both tetracyclines and systemic retinoids have been linked to intracranial hypertension (pseudotumor cerebri). Used together, the risk may be increased, with headache, visual disturbance and papilledema.
この相互作用をわかりやすく説明すると
Omadacycline and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Omadacycline belongs to Anti Bacterial; Tretinoin belongs to Dermatology.
なぜ起こるのか
Possible additive effect on intracranial pressure; the mechanism is not well established.
対処法
Avoid combining oral tretinoin with tetracyclines where an alternative antibiotic exists. If combined, monitor for headache and visual changes and stop treatment if intracranial hypertension is suspected.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OmadacyclineとTretinoinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Tretinoinのその他の相互作用
Omadacyclineのその他の相互作用
よくある質問
Can I take Omadacycline with Tretinoin?
MediHelp rates the interaction as major. Omadacycline and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both tetracyclines and systemic retinoids have been linked to intracranial hypertension (pseudotumor cerebri). Used together, the risk may be increased, with headache, visual disturbance and papilledema.
How serious is the interaction between Omadacycline and Tretinoin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining oral tretinoin with tetracyclines where an alternative antibiotic exists. If combined, monitor for headache and visual changes and stop treatment if intracranial hypertension is suspected.
What other medicines interact with Tretinoin?
MediHelp also lists interactions of Tretinoin with, for example, Doxycycline, Minocycline, Palovarotene. The full list is on the Tretinoin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
